SPR plus

SPR+ detection

The Sierra SPR Pro series as well as the Bruker SPR #64 employs the Surface Plasmon resonance imaging detection called SPR+. SPR+ enables the imaging of 2-dimensional arrays with a level of detection sensitivity normally restricted to linear arrays. SPR+ derives its high sensitivity by combining traditional SPR imaging with high intensity laser light and high-speed optical scanning. The intensity of the light source permits the use of high-speed cameras, which in turn permit more resonance measurements per scan. The net result is lower RMS noise and improved accuracy when measuring small response changes..

brukerBruker Daltonics SPR offers robust, high performance, high throughput analytical and diagnostic biosensors as well as all related consumables and software. As part of the Bruker Corporation, a leading manufacturer of versatile analytical solutions, with offices worldwide, the SPR systems are manufactured in Bremen, Germany.

The usage of the SPR+ detection technology, combined with the company’s Hydrodynamic Isolation™ sample delivery technology, has enabled the development of Bruker’s SPR platforms.

In 2018 the Sierra SPR-32 was launched, followed by the introduction of the Pro series (Sierra SPR 32/24 Pro) in 2020/21 and now the SPR #64 instruments complements Bruker’s SPR offering.


The SPR #64 instrument, introduced in 2024, addresses primary needs of the userbase: achieving both increased sample readout as well as enhanced sample capacity without compromising data quality.


Bruker’s Analytical Biosensors, and the related software packages (data capturing as well as processing) allow researchers to monitor and characterize the interactions of a wide variety of biologic molecules and chemical compounds.